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Last updated: 2017/11/12

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PLA2G2A rabbit monoclonal antibody

  • Catalog # : H00005320-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human PLA2G2A peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human PLA2G2A is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human PLA2G2A peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 5320
  • Gene Name:
  • PLA2G2A
  • Gene Alias:
  • MOM1,PLA2,PLA2B,PLA2L,PLA2S,PLAS1,sPLA2
  • Gene Description:
  • phospholipase A2, group IIA (platelets, synovial fluid)
  • Gene Summary:
  • The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene
  • Other Designations:
  • OTTHUMP00000002786,phosphatidylcholine 2-acylhydrolase,phospholipase A2, group IIA,synovial phospholipase-A2
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