PLA2G2A rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human PLA2G2A peptide using ARM Technology.
Immunogen
A synthetic peptide of human PLA2G2A is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human PLA2G2A peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — PLA2G2A
Entrez GeneID
5320GeneBank Accession#
PLA2G2AGene Name
PLA2G2A
Gene Alias
MOM1, PLA2, PLA2B, PLA2L, PLA2S, PLAS1, sPLA2
Gene Description
phospholipase A2, group IIA (platelets, synovial fluid)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene
Other Designations
OTTHUMP00000002786|phosphatidylcholine 2-acylhydrolase|phospholipase A2, group IIA|synovial phospholipase-A2
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