PLA2G1B monoclonal antibody (M01), clone 1B3
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant PLA2G1B.
Immunogen
PLA2G1B (AAH05386, 17 a.a. ~ 70 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
SGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPVDELDKQKQRV
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (31.68 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PLA2G1B is approximately 0.3ng/ml as a capture antibody.ELISA
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Gene Info — PLA2G1B
Entrez GeneID
5319GeneBank Accession#
BC005386Protein Accession#
AAH05386Gene Name
PLA2G1B
Gene Alias
MGC119834, MGC119835, PLA2, PLA2A, PPLA2
Gene Description
phospholipase A2, group IB (pancreas)
Omim ID
172410Gene Ontology
HyperlinkGene Summary
Phospholipase A2 (EC 3.1.1.4) catalyzes the release of fatty acids from glycero-3-phosphocholines. The best known varieties are the digestive enzymes secreted as zymogens by the pancreas of mammals. Sequences of pancreatic PLA2 enzymes from a variety of mammals have been reported. One striking feature of these enzymes is their close homology to venom phospholipases of snakes. Other forms of PLA2 have been isolated from brain, liver, lung, spleen, intestine, macrophages, leukocytes, erythrocytes, inflammatory exudates, chondrocytes, and platelets (Seilhamer et al., 1986 [PubMed 3028739]) .[supplied by OMIM
Other Designations
phospholipase A2, group IB
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Interactome
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