PKP1 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
PKP1 transfected lysate.
Western Blot
Lane 1: PKP1 transfected lysate ( 79.97 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-PKP1 full-length
Host
Human
Theoretical MW (kDa)
79.97
Interspecies Antigen Sequence
Mouse (95); Rat (95)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-PKP1 antibody (H00005317-B01) by Western Blots.
SDS-PAGE Gel
PKP1 transfected lysate.
Western Blot
Lane 1: PKP1 transfected lysate ( 79.97 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — PKP1
Entrez GeneID
5317GeneBank Accession#
NM_001005337.1Protein Accession#
NP_001005337.1Gene Name
PKP1
Gene Alias
B6P, MGC138829
Gene Description
plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may be involved in molecular recruitment and stabilization during desmosome formation. Mutations in this gene have been associated with the ectodermal dysplasia/skin fragility syndrome. [provided by RefSeq
Other Designations
OTTHUMP00000033848|OTTHUMP00000033849|band 6 protein|plakophilin 1
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Interactome
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Disease
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