PKP1 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human PKP1 partial ORF ( NP_000290, 61 a.a. - 159 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
TLSHSNRGSMYDGLADNYNYGTTSRSSYYSKFQAGNGSWGYPIYNGTLKREPDNRRFSSYSQMENWSRHYPRGSCNTTGAGSDICFMQKIKASRSEPDL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.63
Interspecies Antigen Sequence
Mouse (96); Rat (96)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PKP1
Entrez GeneID
5317GeneBank Accession#
NM_000299Protein Accession#
NP_000290Gene Name
PKP1
Gene Alias
B6P, MGC138829
Gene Description
plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may be involved in molecular recruitment and stabilization during desmosome formation. Mutations in this gene have been associated with the ectodermal dysplasia/skin fragility syndrome. [provided by RefSeq
Other Designations
OTTHUMP00000033848|OTTHUMP00000033849|band 6 protein|plakophilin 1
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Disease
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