PKD2 DNAxPab
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human PKD2 DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — PKD2
Entrez GeneID
5311GeneBank Accession#
BC111454.3Protein Accession#
AAI11455.1Gene Name
PKD2
Gene Alias
APKD2, MGC138466, MGC138468, PC2, PKD4
Gene Description
polycystic kidney disease 2 (autosomal dominant)
Omim ID
173910Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. The encoded protein may function in renal tubular development, morphology, and function, and may modulate intracellular calcium homoeostasis and other signal transduction pathways. This protein interacts with polycystin 1 to produce cation-permeable currents. Mutations in this gene have been associated with autosomal dominant polycystic kidney disease. [provided by RefSeq
Other Designations
polycystin 2|polycystwin
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Interactome
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Disease
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