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Last updated: 2016/12/4
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PITX2 polyclonal antibody (A03)

  • Catalog # : H00005308-A03
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a partial recombinant PITX2.
  • Immunogen:
  • PITX2 (NP_700476, 189 a.a. ~ 270 a.a) partial recombinant protein with GST tag.
  • Sequence:
  • PGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSACQYAVDRP
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.

    QC Testing of H00005308-A03
    Western Blot detection against Immunogen (35.13 KDa) .
  • Storage Buffer:
  • 50 % glycerol
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Recombinant protein)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 5308
  • Gene Name:
  • PITX2
  • Gene Alias:
  • ARP1,Brx1,IDG2,IGDS,IGDS2,IHG2,IRID2,MGC111022,MGC20144,Otlx2,PTX2,RGS,RIEG,RIEG1,RS
  • Gene Description:
  • paired-like homeodomain 2
  • Gene Summary:
  • This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000163736,all1-responsive gene 1,paired-like homeodomain transcription factor 2,pituitary homeo box 2,rieg bicoid-related homeobox transcription factor 1,solurshin
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