PHKA1 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human PHKA1 partial ORF ( NP_002628, 631 a.a. - 730 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
DYDDNYDYLESGNWMNDYDSTSHARCGDEVARYLDHLLAHTAPHPKLAPTSQKGGLDRFQAAVQTTCDLMSLVTKAKELHVQNVHMYLPTKLFQASRPSF
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (88)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PHKA1
Entrez GeneID
5255GeneBank Accession#
NM_002637Protein Accession#
NP_002628Gene Name
PHKA1
Gene Alias
MGC132604, PHKA
Gene Description
phosphorylase kinase, alpha 1 (muscle)
Gene Ontology
HyperlinkGene Summary
The PHKA1 gene encodes the alpha subunit of muscle phosphorylase kinase (EC 2.7.1.38), a key regulatory enzyme of glycogen metabolism. Phosphorylase kinase consists of 4 copies of an alpha-beta-gamma-delta tetramer. The alpha, beta (PHKB; MIM 172490), and gamma (PHKG1; MIM 172470 and PHKG2; MIM 172471) subunits have several isoforms; the delta subunit is calmodulin (CALM1; MIM 114180). PHKA2 (MIM 306000) encodes the alpha subunit of liver-specific phosphorylase kinase and is also located on the X chromosome.[supplied by OMIM
Other Designations
OTTHUMP00000024287|phosphorylase kinase, alpha 1 (muscle), muscle glycogenosis
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Interactome
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Pathway
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