PHF1 monoclonal antibody (M02), clone 4D8
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More Files
- More Functions
Western Blot (Cell lysate)
PHF1 monoclonal antibody (M02), clone 4D8 Western Blot analysis of PHF1 expression in K-562 ( Cat # L009V1 ).
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PHF1 is approximately 1ng/ml as a capture antibody.
Western Blot detection against Immunogen (36.63 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PHF1.
Immunogen
PHF1 (NP_077084, 2 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
AQPPRLSRSGASSLWDPASPAPTSGPRPRLWEGQDVLARWTDGLLYLGTIKKVDSAREVCLVQFEDDSQFLVLWKDISPAALPGEELLCCVCRSETVVP
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (97); Rat (97)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
PHF1 monoclonal antibody (M02), clone 4D8 Western Blot analysis of PHF1 expression in K-562 ( Cat # L009V1 ).Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PHF1 is approximately 1ng/ml as a capture antibody.ELISA
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Gene Info — PHF1
Entrez GeneID
5252GeneBank Accession#
NM_024165Protein Accession#
NP_077084Gene Name
PHF1
Gene Alias
MTF2L2, PCL1, PHF2
Gene Description
PHD finger protein 1
Omim ID
602881Gene Ontology
HyperlinkGene Summary
This gene encodes a Polycomb group protein. The protein is a component of a histone H3 lysine-27 (H3K27)-specific methyltransferase complex, and functions in transcriptional repression of homeotic genes. The protein is also recruited to double-strand breaks, and reduced protein levels results in X-ray sensitivity and increased homologous recombination. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000029139|OTTHUMP00000029140
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Interactome
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Disease
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