PFKP polyclonal antibody (A01)
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Specifications
Product Description
Mouse polyclonal antibody raised against a partial recombinant PFKP.
Immunogen
PFKP (NP_002618, 692 a.a. ~ 783 a.a) partial recombinant protein with GST tag.
Sequence
RAMEWITAKLKEARGRGKKFTTDDSICVLGISKRNVIFQPVAELKKQTDFEHRIPKEQWWLKLRPLMKILAKYKASYDVSDSGQLEHVQPWS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (79); Rat (74)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.23 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
PFKP polyclonal antibody (A01), Lot # 060626JCS1 Western Blot analysis of PFKP expression in MES-SA/Dx5 ( Cat # L021V1 ).Western Blot (Recombinant protein)
ELISA
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Gene Info — PFKP
Entrez GeneID
5214GeneBank Accession#
NM_002627Protein Accession#
NP_002618Gene Name
PFKP
Gene Alias
FLJ40226, PFK-C, PFKF
Gene Description
phosphofructokinase, platelet
Omim ID
171840Gene Ontology
HyperlinkGene Summary
The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM; MIM 610681) and liver (PFKL; MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2.[supplied by OMIM
Other Designations
OTTHUMP00000018966|Phosphofructokinase, platelet type
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Interactomes
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Pathways
- Biosynthesis of alkaloids derived from histidine and purine
- Biosynthesis of alkaloids derived from ornithine
- Biosynthesis of alkaloids derived from shikimate pathway
- Biosynthesis of alkaloids derived from terpenoid and polyketide
- Biosynthesis of phenylpropanoids
- Biosynthesis of plant hormones
- Biosynthesis of terpenoids and steroids
- Fructose and mannose metabolism
- Galactose metabolism
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