PFKFB3 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
PFKFB3 MaxPab rabbit polyclonal antibody. Western Blot analysis of PFKFB3 expression in human kidney.
Western Blot (Transfected lysate)
Western Blot analysis of PFKFB3 expression in transfected 293T cell line (H00005209-T01) by PFKFB3 MaxPab polyclonal antibody.
Lane 1: PFKFB3 transfected lysate(59.60 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human PFKFB3 protein.
Immunogen
PFKFB3 (NP_004557.1, 1 a.a. ~ 520 a.a) full-length human protein.
Sequence
MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLNWIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQIAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNSAEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLMNIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQLKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTGESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKLTPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFEEHVASTSAALPSCLPPEVPTQLPGQNMKGSRSSADSSRKH
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (98); Rat (92)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
PFKFB3 MaxPab rabbit polyclonal antibody. Western Blot analysis of PFKFB3 expression in human kidney.Western Blot (Transfected lysate)
Western Blot analysis of PFKFB3 expression in transfected 293T cell line (H00005209-T01) by PFKFB3 MaxPab polyclonal antibody.
Lane 1: PFKFB3 transfected lysate(59.60 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — PFKFB3
Entrez GeneID
5209GeneBank Accession#
NM_004566.2Protein Accession#
NP_004557.1Gene Name
PFKFB3
Gene Alias
IPFK2, PFK2
Gene Description
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
Omim ID
605319Gene Ontology
HyperlinkGene Summary
O
Other Designations
6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase|6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase|OTTHUMP00000019040|OTTHUMP00000044861|fructose-6-phosphate,2-kinase/fructose-2, 6-bisphosphatase|inducible 6-phosphofructo-2-kinase/fructose-2,6-bi
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Interactome
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Pathway
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Disease
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Publication Reference
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Reduced methylation of PFKFB3 in cancer cells shunts glucose towards the pentose phosphate pathway.
Yamamoto T, Takano N, Ishiwata K, Ohmura M, Nagahata Y, Matsuura T, Kamata A, Sakamoto K, Nakanishi T, Kubo A, Hishiki T, Suematsu M.
Nature Communications 2014 Mar; 5:3480.
Application：WB-Ce, WB-Tr, Human, HEK 293, HeLa, U937, HCT116 cells.
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Reduced methylation of PFKFB3 in cancer cells shunts glucose towards the pentose phosphate pathway.
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