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Last updated: 2016/11/27

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PFKFB2 (Human) Recombinant Protein (Q01)

  • Catalog # : H00005208-Q01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Human PFKFB2 partial ORF ( NP_006203, 406 a.a. - 505 a.a.) recombinant protein with GST-tag at N-terminal.
  • Sequence:
  • GADELPYLRCPLHTIFKLTPVAYGCKVETIKLNVEAVNTHRDKPTNNFPKNQTPVRMRRNSFTPLSSSNTIRRPRNYSVGSRPLKPLSPLRAQDMQEGAD
  • Host:
  • Wheat Germ (in vitro)
  • Theoretical MW (kDa):
  • 36.74
  • Purification:
  • Glutathione Sepharose 4 Fast Flow
  • Quality Control Testing:
  • 12.5% SDS-PAGE Stained with Coomassie Blue.

    QC Testing of H00005208-Q01
  • Storage Buffer:
  • 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Best use within three months from the date of receipt of this protein.
  • Applications
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Application Image
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Gene Information
  • Entrez GeneID:
  • 5208
  • Gene Name:
  • PFKFB2
  • Gene Alias:
  • DKFZp781D2217,MGC138308,MGC138310,PFK-2/FBPase-2
  • Gene Description:
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
  • Gene Summary:
  • The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2,6PF-2-K/Fru-2,6-P2ASE heart-type isozyme,OTTHUMP00000034285,OTTHUMP00000034286,PFKFB, cardiac,fructose-2,6-bisphosphatase, cardiac isozyme
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