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PFKFB1 Pre-design Chimera RNAi

  • Catalog # : H00005207-R03
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Homo sapiens 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 (PFKFB1), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_002625
  • Target Region:
  • Coding sequence
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 5207
  • Gene Name:
  • PFKFB1
  • Gene Alias:
  • F6PK,HL2K,MGC116715,MGC116717,PFRX
  • Gene Description:
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
  • Gene Summary:
  • This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. [provided by RefSeq
  • Other Designations:
  • 6PF-2-K/Fru-2,6-P2ASE liver isozyme,OTTHUMP00000023391,fructose-2,6-bisphosphatase,fructose-6-phosphate,2-kinase:fructose-2,6-bisphosphatase
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