ATP8B1 monoclonal antibody (M02), clone 3F10
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More Files
- More Functions
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged ATP8B1 is 1 ng/ml as a capture antibody.
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant ATP8B1.
Immunogen
ATP8B1 (NP_005594.1, 471 a.a. ~ 551 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
INGQIYGDHRDASQHNHNKIEQVDFSWNTYADGKLAFYDHYLIEQIQSGKEPEVRQFFFLLAVCHTVMVDRTDGQLNYQAA
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (89); Rat (88)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged ATP8B1 is 1 ng/ml as a capture antibody.ELISA
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Gene Info — ATP8B1
Entrez GeneID
5205GeneBank Accession#
NM_005603Protein Accession#
NP_005594.1Gene Name
ATP8B1
Gene Alias
ATPIC, BRIC, FIC1, PFIC, PFIC1
Gene Description
ATPase, class I, type 8B, member 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the P-type cation transport ATPase family, which belongs to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to another. Mutations in this gene may result in progressive familial intrahepatic cholestasis type 1 and in benign recurrent intrahepatic cholestasis. [provided by RefSeq
Other Designations
E1-E2 ATPase|OTTHUMP00000163615|phospholipid-transporting ATPase IC
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Interactome
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Disease
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