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Last updated: 2017/6/25

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CFP Pre-design Chimera RNAi

  • Catalog # : H00005199-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens complement factor properdin (CFP), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_002621
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 5199
  • Gene Name:
  • CFP
  • Gene Alias:
  • BFD,PFC,PFD,PROPERDIN
  • Gene Description:
  • complement factor properdin
  • Gene Summary:
  • This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified
  • Other Designations:
  • properdin P factor, complement
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