CFP (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human CFP partial ORF ( AAH15756.1, 213 a.a. - 334 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
PHEPKETRSRKCSAPEPSQKPPGKPCPGLAYEQRRCTGLPPCPVAGGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTHICNTAVPCPVDGEWDSWGEWSPCIRRNMKS
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
39.16
Interspecies Antigen Sequence
Mouse (75); Rat (79)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CFP
Entrez GeneID
5199GeneBank Accession#
BC015756Protein Accession#
AAH15756.1Gene Name
CFP
Gene Alias
BFD, PFC, PFD, PROPERDIN
Gene Description
complement factor properdin
Gene Ontology
HyperlinkGene Summary
This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified
Other Designations
properdin P factor, complement
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Interactome
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Disease
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