PEX14 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-PEX14 full-length
Host
Human
Theoretical MW (kDa)
41.2
Interspecies Antigen Sequence
Mouse (92); Rat (92)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-PEX14 antibody (H00005195-B01) by Western Blots.
SDS-PAGE Gel
PEX14 transfected lysate.
Western Blot
Lane 1: PEX14 transfected lysate ( 41.2 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — PEX14
Entrez GeneID
5195GeneBank Accession#
NM_004565Protein Accession#
NP_004556Gene Name
PEX14
Gene Alias
MGC12767, NAPP2, Pex14p, dJ734G22.2
Gene Description
peroxisomal biogenesis factor 14
Gene Ontology
HyperlinkGene Summary
This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome. [provided by RefSeq
Other Designations
NF-E2 associated polypeptide 2|OTTHUMP00000001902|PTS1 receptor docking protein|peroxin-14|peroxisomal membrane anchor protein Pex14p
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Interactome
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Disease
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