PEX14 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human PEX14 partial ORF ( NP_004556.1, 293 a.a. - 375 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
LGPQEEGEGVVDVKGQVRMEVQGEEEKREDKEDEEDEEDDDVSHVDEEDCLGVQREDRRGGDGQINEQVEKLRRPEGASNESE
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
34.87
Interspecies Antigen Sequence
Mouse (87); Rat (88)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PEX14
Entrez GeneID
5195GeneBank Accession#
NM_004565Protein Accession#
NP_004556.1Gene Name
PEX14
Gene Alias
MGC12767, NAPP2, Pex14p, dJ734G22.2
Gene Description
peroxisomal biogenesis factor 14
Gene Ontology
HyperlinkGene Summary
This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome. [provided by RefSeq
Other Designations
NF-E2 associated polypeptide 2|OTTHUMP00000001902|PTS1 receptor docking protein|peroxin-14|peroxisomal membrane anchor protein Pex14p
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Interactome
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Disease
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