PEX14 monoclonal antibody (M01), clone 1G12
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PEX14.
Immunogen
PEX14 (NP_004556.1, 293 a.a. ~ 375 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
LGPQEEGEGVVDVKGQVRMEVQGEEEKREDKEDEEDEEDDDVSHVDEEDCLGVQREDRRGGDGQINEQVEKLRRPEGASNESE
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (87); Rat (88)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (34.87 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PEX14 is approximately 3ng/ml as a capture antibody.ELISA
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Gene Info — PEX14
Entrez GeneID
5195GeneBank Accession#
NM_004565Protein Accession#
NP_004556.1Gene Name
PEX14
Gene Alias
MGC12767, NAPP2, Pex14p, dJ734G22.2
Gene Description
peroxisomal biogenesis factor 14
Gene Ontology
HyperlinkGene Summary
This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome. [provided by RefSeq
Other Designations
NF-E2 associated polypeptide 2|OTTHUMP00000001902|PTS1 receptor docking protein|peroxin-14|peroxisomal membrane anchor protein Pex14p
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Interactome
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Disease
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