PEX14 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human PEX14 peptide using ARM Technology.
Immunogen
A synthetic peptide of human PEX14 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human PEX14 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — PEX14
Entrez GeneID
5195GeneBank Accession#
PEX14Gene Name
PEX14
Gene Alias
MGC12767, NAPP2, Pex14p, dJ734G22.2
Gene Description
peroxisomal biogenesis factor 14
Gene Ontology
HyperlinkGene Summary
This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome. [provided by RefSeq
Other Designations
NF-E2 associated polypeptide 2|OTTHUMP00000001902|PTS1 receptor docking protein|peroxin-14|peroxisomal membrane anchor protein Pex14p
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Interactome
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