PEX14 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human PEX14 protein.
Immunogen
PEX14 (NP_004556.1, 1 a.a. ~ 377 a.a) full-length human protein.
Sequence
MASSEQAEQPSQPSSTPGSENVLPREPLIATAVKFLQNSRVRQSPLATRRAFLKKKGLTDEEIDMAFQQSGTAADEPSSLGPATQVVPVQPPHLISQPYSPAGSRWRDYGALAIIMAGIAFGFHQLYKKYLLPLILGGREDRKQLERMEAGLSELSGSVAQTVTQLQTTLASVQELLIQQQQKIQELAHELAAAKATTSTNWILESQNINELKSEINSLKGLLLNRRQFPPSPSAPKIPSWQIPVKSPSPSSPAAVNHHSSSDISPVSNESTSSSPGKEGHSPEGSTVTYHLLGPQEEGEGVVDVKGQVRMEVQGEEEKREDKEDEEDEEDDDVSHVDEEDCLGVQREDRRGGDGQINEQVEKLRRPEGASNESERD
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (92); Rat (92)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
PEX14 MaxPab polyclonal antibody. Western Blot analysis of PEX14 expression in human ovarian cancer.Western Blot (Cell lysate)
PEX14 MaxPab polyclonal antibody. Western Blot analysis of PEX14 expression in HeLa.Western Blot (Transfected lysate)
Western Blot analysis of PEX14 expression in transfected 293T cell line (H00005195-T01) by PEX14 MaxPab polyclonal antibody.
Lane 1: PEX14 transfected lysate(41.47 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to PEX14 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — PEX14
Entrez GeneID
5195GeneBank Accession#
NM_004565.2Protein Accession#
NP_004556.1Gene Name
PEX14
Gene Alias
MGC12767, NAPP2, Pex14p, dJ734G22.2
Gene Description
peroxisomal biogenesis factor 14
Gene Ontology
HyperlinkGene Summary
This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome. [provided by RefSeq
Other Designations
NF-E2 associated polypeptide 2|OTTHUMP00000001902|PTS1 receptor docking protein|peroxin-14|peroxisomal membrane anchor protein Pex14p
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Interactome
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Disease
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