PDHA1 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
PDHA1 MaxPab polyclonal antibody. Western Blot analysis of PDHA1 expression in human kidney.
Western Blot (Tissue lysate)
PDHA1 MaxPab polyclonal antibody. Western Blot analysis of PDHA1 expression in rat brain.
Western Blot (Cell lysate)
PDHA1 MaxPab polyclonal antibody. Western Blot analysis of PDHA1 expression in HepG2.
Western Blot (Cell lysate)
PDHA1 MaxPab polyclonal antibody. Western Blot analysis of PDHA1 expression in HeLa.
Western Blot (Cell lysate)
PDHA1 MaxPab polyclonal antibody. Western Blot analysis of PDHA1 expression in NIH/3T3.
Western Blot (Transfected lysate)
Western Blot analysis of PDHA1 expression in transfected 293T cell line (H00005160-T01) by PDHA1 MaxPab polyclonal antibody.
Lane 1: PDHA1 transfected lysate(43.01 KDa).
Lane 2: Non-transfected lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of purified MaxPab antibody to PDHA1 on formalin-fixed paraffin-embedded human stomach. [antibody concentration 1.5 ug/ml]
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human PDHA1 protein.
Immunogen
PDHA1 (AAH02406, 1 a.a. ~ 390 a.a) full-length human protein.
Sequence
MRKMLAAVSRVLSGASQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPPLEELGYHIYSSDPPFEVRGANQWIKFKSVS
Host
Mouse
Reactivity
Human, Mouse, Rat
Interspecies Antigen Sequence
Mouse (98); Rat (98)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
PDHA1 MaxPab polyclonal antibody. Western Blot analysis of PDHA1 expression in human kidney.Western Blot (Tissue lysate)
PDHA1 MaxPab polyclonal antibody. Western Blot analysis of PDHA1 expression in rat brain.Western Blot (Cell lysate)
PDHA1 MaxPab polyclonal antibody. Western Blot analysis of PDHA1 expression in HepG2.Western Blot (Cell lysate)
PDHA1 MaxPab polyclonal antibody. Western Blot analysis of PDHA1 expression in HeLa.Western Blot (Cell lysate)
PDHA1 MaxPab polyclonal antibody. Western Blot analysis of PDHA1 expression in NIH/3T3.Western Blot (Transfected lysate)
Western Blot analysis of PDHA1 expression in transfected 293T cell line (H00005160-T01) by PDHA1 MaxPab polyclonal antibody.
Lane 1: PDHA1 transfected lysate(43.01 KDa).
Lane 2: Non-transfected lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of purified MaxPab antibody to PDHA1 on formalin-fixed paraffin-embedded human stomach. [antibody concentration 1.5 ug/ml] -
Gene Info — PDHA1
Entrez GeneID
5160GeneBank Accession#
BC002406Protein Accession#
AAH02406Gene Name
PDHA1
Gene Alias
PDHA, PDHCE1A, PHE1A
Gene Description
pyruvate dehydrogenase (lipoamide) alpha 1
Gene Ontology
HyperlinkGene Summary
The pyruvate dehydrogenase complex is a nuclear-encoded mitochondrial matrix multienzyme complex that provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle by catalyzing the irreversible conversion of pyruvate into acetyl-CoA. The PDH complex is composed of multiple copies of 3 enzymes: E1 (PDHA1); dihydrolipoyl transacetylase (DLAT; MIM 608770) (E2; EC 2.3.1.12); and dihydrolipoyl dehydrogenase (DLD; MIM 238331) (E3; EC 1.8.1.4). The E1 enzyme is a heterotetramer of 2 alpha and 2 beta subunits. The E1-alpha subunit contains the E1 active site and plays a key role in the function of the PDH complex (Brown et al., 1994 [PubMed 7853374]).[supplied by OMIM
Other Designations
OTTHUMP00000023015|pyruvate dehydrogenase E1 alpha subunit
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Interactome
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Pathway
- Biosynthesis of alkaloids derived from histidine and purine
- Biosynthesis of alkaloids derived from ornithine
- Biosynthesis of alkaloids derived from shikimate pathway
- Biosynthesis of alkaloids derived from terpenoid and polyketide
- Biosynthesis of phenylpropanoids
- Biosynthesis of plant hormones
- Biosynthesis of terpenoids and steroids
- Butanoate metabolism
- Citrate cycle (TCA cycle)
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