PDE1B monoclonal antibody (M01), clone 5B6
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PDE1B.
Immunogen
PDE1B (AAH32226, 437 a.a. ~ 536 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
TDVAEKSVQPLADEDSKSKNQPSFQWRQPSLDVEVGDPNPDVVSFRSTWVKRIQENKQKWKERAASGITNQMSIDELSPCEEEAPPSPAEDEHNQNGNLD
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (92); Rat (93)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PDE1B is approximately 0.03ng/ml as a capture antibody.ELISA
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Gene Info — PDE1B
Entrez GeneID
5153GeneBank Accession#
BC032226Protein Accession#
AAH32226Gene Name
PDE1B
Gene Alias
PDE1B1, PDES1B
Gene Description
phosphodiesterase 1B, calmodulin-dependent
Omim ID
171891Gene Ontology
HyperlinkGene Summary
O
Other Designations
Phosphodiesterase-1B|calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase|calmodulin-stimulated phosphodiesterase PDE1B1|phosphodiesterase IB, calmodulin-dependent|presumed 63kDa form of the type 1 cyclic nucleotide phosphodiesterase family k
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Interactome
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Pathway
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Disease
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Publication Reference
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Distinct metabolism of cyclic adenosine monophosphate in regulatory and helper CD4(+) T cells.
Bazhin AV, Kahnert S, Kimpfler S, Schadendorf D, Umansky V.
Molecular Immunology 2009 Nov; 47(4):678.
Application:WB-Ce, Mouse, Mouse regulatory and conventional CD4+ T cells.
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Distinct metabolism of cyclic adenosine monophosphate in regulatory and helper CD4(+) T cells.
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