PDE9A monoclonal antibody (M01), clone 1E1
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PDE9A.
Immunogen
PDE9A (NP_001001567.1, 434 a.a. ~ 533 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
EGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (84); Rat (82)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to PDE9A on formalin-fixed paraffin-embedded human cerebellum. [antibody concentration 3 ug/ml]Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PDE9A is 1 ng/ml as a capture antibody.ELISA
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Gene Info — PDE9A
Entrez GeneID
5152GeneBank Accession#
NM_001001567Protein Accession#
NP_001001567.1Gene Name
PDE9A
Gene Alias
HSPDE9A2
Gene Description
phosphodiesterase 9A
Omim ID
602973Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene catalyzes the hydrolysis of cAMP and cGMP to their corresponding monophosphates. The encoded protein plays a role in signal transduction by regulating the intracellular concentration of these cyclic nucleotides. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq
Other Designations
CGMP-specific 3',5'-cyclic phosphodiesterase type 9|OTTHUMP00000109390|OTTHUMP00000109391|OTTHUMP00000109393|OTTHUMP00000109394|OTTHUMP00000109397|OTTHUMP00000109399|OTTHUMP00000109400|phosphodiesterase PDE9A21
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Interactome
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Pathway
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Disease
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