PDE4D (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human PDE4D partial ORF ( NP_006194.2, 581 a.a. - 673 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
SPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
35.97
Interspecies Antigen Sequence
Rat (85)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PDE4D
Entrez GeneID
5144GeneBank Accession#
NM_006203Protein Accession#
NP_006194.2Gene Name
PDE4D
Gene Alias
DPDE3, HSPDE4D, PDE4DN2, STRK1
Gene Description
phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila)
Gene Ontology
HyperlinkGene Summary
This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins
Other Designations
cAMP-specific phosphodiesterase 4D|cAMP-specific phosphodiesterase PDE4D6|dunce-like phosphodiesterase E3|phosphodiesterase 4D, cAMP-specific (dunce
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Interactome
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Pathway
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Disease
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