PDE3A monoclonal antibody (M03), clone 2D7
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PDE3A.
Immunogen
PDE3A (NP_000912, 533 a.a. ~ 640 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
TPASSLVSKISAVQFPESADTTAKQSLGSHRALTYTQSAPDLSPQILTPPVICSSCGRPYSQGNPADEPLERSGVATRTPSRTDDTAQVTSDYETNNNSDSSDIVQNE
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (76); Rat (77)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.62 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
-
Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PDE3A is 0.1 ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to PDE3A on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — PDE3A
Entrez GeneID
5139GeneBank Accession#
NM_000921Protein Accession#
NP_000912Gene Name
PDE3A
Gene Alias
CGI-PDE
Gene Description
phosphodiesterase 3A, cGMP-inhibited
Omim ID
123805Gene Ontology
HyperlinkGene Summary
O
Other Designations
cGMP-inhibited 3',5'-cyclic phosphodiesterase A|cyclic GMP inhibited phosphodiesterase A
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
A pathophysiological role of PDE3 in allergic airway inflammation.
Beute J, Lukkes M, Koekoek EP, Nastiti H, Ganesh K, de Bruijn MJ, Hockman S, van Nimwegen M, Braunstahl GJ, Boon L, Lambrecht BN, Manganiello VC, Hendriks RW, KleinJan A.
JCI Insight 2018 Jan; 3(2):94888.
Application:IHC, Human, Human bronchial biopsies.
-
A pathophysiological role of PDE3 in allergic airway inflammation.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com