Immunoprecipitation of PDCD2 transfected lysate using anti-PDCD2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with PDCD2 MaxPab rabbit polyclonal antibody (D01) (H00005134-D01).
This gene encodes a nuclear protein expressed in a variety of tissues. The rat homolog, Rp8, is transiently expressed in immature thymocytes and is thought to be involved in programmed cell death. Expression of the human gene has been shown to be repressed by BCL6, a transcriptional repressor required for lymph node germinal center development, suggesting that BCL6 regulates apoptosis by its effects on PDCD2. This gene is closely linked on chromosome 6 to the gene for TBP, the TATA binding protein. Two transcripts encoding different proteins have been identified. [provided by RefSeq
OTTHUMP00000017701,programmed cell death 2/Rp8 homolog,zinc finger protein Rp-8