PDCD1 purified MaxPab rabbit polyclonal antibody (D01P)
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human PDCD1 protein.
Immunogen
PDCD1 (AAH74740.1, 1 a.a. ~ 288 a.a) full-length human protein.
Sequence
MQIPQAPWPVVWAVLQLGWRPGWFLDSPDRPWNPPTFSPALLVVTEGDNATFTCSFSNTSESFVLNWYRMSPSNQTDKLAAFPEDRSQPGQDCRFRVTQLPNGRDFHMSVVRARRNDSGTYLCGAISLAPKAQIKESLRAELRVTERRAEVPTAHPSPSPRPAGQFQTLVVGVVGGLLGSLVLLVWVLAVICSRAARGTIGARRTGQPLKEDPSAVPVFSVDYGELDFQWREKTPEPPVPCVPEQTEYATIVFPSGMGTSSPARRGSADGPRSAQPLRPEDGHCSWPL
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (59); Rat (61)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of PDCD1 expression in transfected 293T cell line (H00005133-T01) by PDCD1 MaxPab polyclonal antibody.
Lane 1: PDCD1 transfected lysate(31.60 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — PDCD1
Entrez GeneID
5133GeneBank Accession#
BC074740Protein Accession#
AAH74740.1Gene Name
PDCD1
Gene Alias
CD279, PD1, SLEB2, hPD-1, hPD-l
Gene Description
programmed cell death 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq
Other Designations
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