PDC DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human PDC DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MSSPQSRNGKDSKERVSRKMSIQEYELIHKEKEDENCLRKYRRQCMQDMHQKLSFGPRYGFVYELETGKQFLETIEKELKITTIVVHIYEDGIKGCDALNSSLTCLAAEYPIVKFCKIKASNTGAGDRFSLDVLPTLLIYKGGELISNFISVAEQFAEEFFAGDVESFLNEYGLLPEREVHVLEHTKIEEEDVE
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — PDC
Entrez GeneID
5132GeneBank Accession#
BC153182.1Protein Accession#
AAI53183.1Gene Name
PDC
Gene Alias
MEKA, PHD, PhLOP, PhLP
Gene Description
phosducin
Omim ID
171490Gene Ontology
HyperlinkGene Summary
This gene encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the retina. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. This gene is a potential candidate gene for retinitis pigmentosa and Usher syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
33kDA phototransducing protein|G beta gamma binding protein|phosducin-like orphan protein
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Interactome
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Pathway
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Disease
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