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Last updated: 2016/10/23

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PCSK5 rabbit monoclonal antibody

  • Catalog # : H00005125-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human PCSK5 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human PCSK5 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human PCSK5 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • Entrez GeneID:
  • 5125
  • GeneBank Accession#:
  • PCSK5
  • Gene Name:
  • PCSK5
  • Gene Alias:
  • PC5,PC6,PC6A,SPC6
  • Gene Description:
  • proprotein convertase subtilisin/kexin type 5
  • Gene Summary:
  • The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Two alternatively spliced transcripts are described for this gene but only one has its full length nature known. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000021497,OTTHUMP00000063532,prohormone convertase 5,proprotein convertase PC5,protease PC6,subtilisin/kexin-like protease PC5
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