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Last updated: 2016/12/4

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PCK2 rabbit monoclonal antibody

  • Catalog # : H00005106-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human PCK2 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human PCK2 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human PCK2 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 5106
  • GeneBank Accession#:
  • PCK2
  • Gene Name:
  • PCK2
  • Gene Alias:
  • PEPCK,PEPCK-M,PEPCK2
  • Gene Description:
  • phosphoenolpyruvate carboxykinase 2 (mitochondrial)
  • Gene Summary:
  • This gene encodes a member of the phosphoenolpyruvate carboxykinase (GTP) family. The protein is a mitochondrial enzyme that catalyzes the conversion of oxaloacetate to phosphoenolpyruvate in the presence of GTP. A cytosolic form encoded by a different gene has also been characterized and is the key enzyme of gluconeogenesis in the liver. The encoded protein may serve a similar function, although it is constitutively expressed and not modulated by hormones such as glucagon and insulin that regulate the cytosolic form. Alternatively spliced transcript variants have been described. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000164700,PEP carboxykinase,mitochondrial phosphoenolpyruvate carboxykinase 2,phosphoenolpyruvate carboxylase,phosphopyruvate carboxylase
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