Immunoprecipitation of PCCB transfected lysate using anti-PCCB MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with PCCB purified MaxPab mouse polyclonal antibody (B01P) (H00005096-B01P).
The protein encoded by this gene is a subunit of the propionyl-CoA carboxylase (PCC) enzyme, which is involved in the catabolism of propionyl-CoA. PCC is a mitochondrial enzyme that probably acts as a dodecamer of six alpha subunits and six beta subunits. This gene encodes the beta subunit of PCC. Defects in this gene are a cause of propionic acidemia type II (PA-2). [provided by RefSeq