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PCCA rabbit monoclonal antibody

  • Catalog # : H00005095-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human PCCA peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human PCCA is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human PCCA peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 5095
  • GeneBank Accession#:
  • PCCA
  • Gene Name:
  • PCCA
  • Gene Alias:
  • -
  • Gene Description:
  • propionyl Coenzyme A carboxylase, alpha polypeptide
  • Gene Summary:
  • The protein encoded by this gene is the alpha subunit of the heterodimeric mitochondrial enzyme Propionyl-CoA carboxylase. PCCA encodes the biotin-binding region of this enzyme. Mutations in either PCCA or PCCB (encoding the beta subunit) lead to an enzyme deficiency resulting in propionic acidemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000018635,PCCase alpha subunit,pccA complementation group,propanoyl-CoA:carbon dioxide ligase alpha subunit,propionyl-CoA carboxylase alpha chain, mitochondrial,propionyl-Coenzyme A carboxylase, alpha polypeptide
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