Western blot analysis of PAX9 over-expressed 293 cell line, cotransfected with PAX9 Validated Chimera RNAi ( Cat # H00005083-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with PAX9 monoclonal antibody (M03), clone 4B9 (Cat # H00005083-M03 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.
This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 9 gene is unknown but it may involve development of stratified squamous epithelia as well as various organs and skeletal elements. [provided by RefSeq