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PAX6 rabbit monoclonal antibody

  • Catalog # : H00005080-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human PAX6 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human PAX6 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human PAX6 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 5080
  • GeneBank Accession#:
  • PAX6
  • Gene Name:
  • PAX6
  • Gene Alias:
  • AN,AN2,D11S812E,MGC17209,MGDA,WAGR
  • Gene Description:
  • paired box 6
  • Gene Summary:
  • This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding either the same or different isoform have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000038833,OTTHUMP00000038834,OTTHUMP00000038835,OTTHUMP00000038836,OTTHUMP00000038837,OTTHUMP00000038838,OTTHUMP00000038839,OTTHUMP00000038840,paired box gene 6,paired box homeotic gene-6
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