PAX6 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
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Specifications
Product Description
Rabbit polyclonal antibody raised against a full-length human PAX6 protein.
Immunogen
PAX6 (NP_000271.1, 1 a.a. ~ 422 a.a) full-length human protein.
Sequence
MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQVPGSEPDMSQYWPRLQ
Host
Rabbit
Reactivity
Human, Mouse
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
PAX6 MaxPab rabbit polyclonal antibody. Western Blot analysis of PAX6 expression in human kidney.Western Blot (Tissue lysate)
PAX6 MaxPab rabbit polyclonal antibody. Western Blot analysis of PAX6 expression in mouse spleen.Western Blot (Transfected lysate)
Western Blot analysis of PAX6 expression in transfected 293T cell line (H00005080-T02) by PAX6 MaxPab polyclonal antibody.
Lane 1: PAX6 transfected lysate(46.70 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — PAX6
Entrez GeneID
5080GeneBank Accession#
NM_000280.2Protein Accession#
NP_000271.1Gene Name
PAX6
Gene Alias
AN, AN2, D11S812E, MGC17209, MGDA, WAGR
Gene Description
paired box 6
Gene Ontology
HyperlinkGene Summary
This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding either the same or different isoform have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000038833|OTTHUMP00000038834|OTTHUMP00000038835|OTTHUMP00000038836|OTTHUMP00000038837|OTTHUMP00000038838|OTTHUMP00000038839|OTTHUMP00000038840|paired box gene 6|paired box homeotic gene-6
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Interactomes
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Pathways
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Diseases
- Abnormalities
- Alcoholism
- Atherosclerosis
- Atrophy
- Autistic Disorder
- Blepharoptosis
- Calcinosis
- Cleft Lip
- Cleft Palate
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Publication Reference
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Downregulation of PAX6 by shRNA Inhibits Proliferation and Cell Cycle Progression of Human Non-Small Cell Lung Cancer Cell Lines.
Zhao X, Yue W, Zhang L, Ma L, Jia W, Qian Z, Zhang C, Wang Y.
PLoS One 2014 Jan; 9(1):e85738.
Application:WB-Tr, Human, A-549, H1299 cells.
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Downregulation of PAX6 by shRNA Inhibits Proliferation and Cell Cycle Progression of Human Non-Small Cell Lung Cancer Cell Lines.
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