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PAX5 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00005079-T02
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-PAX5 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 42.1
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-PAX5 antibody (H00005079-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00005079-T02
    PAX5 transfected lysate.
    Western Blot
    QC Testing of H00005079-T02
    Lane 1: PAX5 transfected lysate ( 42.10 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 5079
  • Gene Name:
  • PAX5
  • Gene Alias:
  • BSAP
  • Gene Description:
  • paired box 5
  • Gene Summary:
  • This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9;14)(p13;q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternatively spliced transcript variants encoding different isoforms have been described but their biological validity has not been determined. [provided by RefSeq
  • Other Designations:
  • B-cell lineage specific activator,paired box homeotic gene 5,transcription factor PAX 5
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