PAX3 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-PAX3 full-length
Host
Human
Theoretical MW (kDa)
53.5
Interspecies Antigen Sequence
Mouse (99); Rat (99)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-PAX3 antibody (H00005077-D01P) by Western Blots.
SDS-PAGE Gel
PAX3 transfected lysate.
Western Blot
Lane 1: PAX3 transfected lysate ( 53.50 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — PAX3
Entrez GeneID
5077GeneBank Accession#
NM_181458.1Protein Accession#
NP_852123.1Gene Name
PAX3
Gene Alias
CDHS, HUP2, MGC120381, MGC120382, MGC120383, MGC120384, MGC134778, WS1
Gene Description
paired box 3
Gene Ontology
HyperlinkGene Summary
This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini. [provided by RefSeq
Other Designations
paired box homeotic gene 3|paired domain gene 3|paired domain gene HuP2
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Interactome
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Disease
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