PAWR (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human PAWR partial ORF ( NP_002574, 231 a.a. - 340 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
SVSEEDVSSRYSRTDRSGFPRYNRDANVSGTLVSSSTLEKKIEDLEKEVVRERQENLRLVRLMQDKEEMIGKLKEEIDLLNRDLDDIEDENEQLKQENKTLLKVVGQLTR
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.84
Interspecies Antigen Sequence
Mouse (85)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PAWR
Entrez GeneID
5074GeneBank Accession#
NM_002583Protein Accession#
NP_002574Gene Name
PAWR
Gene Alias
PAR4, Par-4
Gene Description
PRKC, apoptosis, WT1, regulator
Omim ID
601936Gene Ontology
HyperlinkGene Summary
The tumor suppressor WT1 represses and activates transcription. The protein encoded by this gene is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells. [provided by RefSeq
Other Designations
WT1-interacting protein|prostate apoptosis response protein 4|prostate apoptosis response protein PAR-4|transcriptional repressor PAR4
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Interactome
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Disease
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