PARK2 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
- More Functions
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-PARK2 full-length
Host
Human
Theoretical MW (kDa)
42.4
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-PARK2 antibody (H00005071-B01) by Western Blots.
SDS-PAGE Gel
PARK2 transfected lysate.
Western Blot
Lane 1: PARK2 transfected lysate ( 42.4 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — PARK2
Entrez GeneID
5071GeneBank Accession#
BC022014.2Protein Accession#
-Gene Name
PARK2
Gene Alias
AR-JP, LPRS2, PDJ, PRKN
Gene Description
Parkinson disease (autosomal recessive, juvenile) 2, parkin
Gene Ontology
HyperlinkGene Summary
The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq
Other Designations
E3 ubiquitin ligase|OTTHUMP00000017565|OTTHUMP00000017566|OTTHUMP00000017567|parkin|parkin 2
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Interactome
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Pathway
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Disease
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