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Last updated: 2017/1/15

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PAM rabbit monoclonal antibody

  • Catalog # : H00005066-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human PAM peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human PAM is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human PAM peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 5066
  • GeneBank Accession#:
  • PAM
  • Gene Name:
  • PAM
  • Gene Alias:
  • PAL,PHM
  • Gene Description:
  • peptidylglycine alpha-amidating monooxygenase
  • Gene Summary:
  • This gene encodes a multifunctional protein. It has two enzymatically active domains with catalytic activities - peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL). These catalytic domains work sequentially to catalyze neuroendocrine peptides to active alpha-amidated products. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene but some of their full length sequences are not yet known. [provided by RefSeq
  • Other Designations:
  • pancreatic peptidylglycine alpha-amidating monooxygenase,peptidyl alpha-amidating enzyme,peptidyl-alpha-hydroxyglycine alpha-amidating lyase,peptidylglycine 2-hydroxylase,peptidylglycine alpha-hydroxylating monooxygenase
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