PRDX1 monoclonal antibody (M01), clone 4B11-D10
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More Files
- More Functions
Western Blot (Cell lysate)
PRDX1 monoclonal antibody (M01), clone 4B11-D10 Western Blot analysis of PRDX1 expression in HeLa ( Cat # L013V1 ).
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PRDX1 is approximately 1ng/ml as a capture antibody.
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant PRDX1.
Immunogen
PRDX1 (AAH07063, 1 a.a. ~ 199 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFHPLDFTFVCPTEIIAFSDRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKSKEYFSKQK
Host
Mouse
Reactivity
Human
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
PRDX1 monoclonal antibody (M01), clone 4B11-D10 Western Blot analysis of PRDX1 expression in HeLa ( Cat # L013V1 ).Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PRDX1 is approximately 1ng/ml as a capture antibody.ELISA
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Gene Info — PRDX1
Entrez GeneID
5052GeneBank Accession#
BC007063Protein Accession#
AAH07063Gene Name
PRDX1
Gene Alias
MSP23, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2
Gene Description
peroxiredoxin 1
Omim ID
176763Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Three transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000009234|natural killer-enhancing factor A|proliferation-associated gene A|thioredoxin-dependent peroxide reductase 2
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Interactome
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Disease
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Publication Reference
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The KHENERGY Study: Safety and Efficacy of KH176 in Mitochondrial m.3243A>G Spectrum Disorders.
Janssen MC, Koene S, de Laat P, Hemelaar P, Pickkers P, Spaans E, Beukema R, Beyrath J, Groothuis J, Verhaak C, Smeitink J.
Clinical Pharmacology and Therapeutics 2019 Jan; 105(1):101.
Application：ELISA, Human, Plasma.
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Peroxiredoxin 1 expression in active ulcerative colitis mucosa identified by proteome analysis and involvement of thioredoxin based on immunohistochemistry.
Horie K, Mikami T, Yoshida T, Sato Y, Okayasu I.
Oncology Letters 2018 Feb; 15(2):2364.
Application：IHC, WB, Human, Sigmoid colon, Rectum.
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Induced nitric oxide synthetase and peroxiredoxin expression in intramucosal poorly differentiated gastric cancer of young patients.
Hirahashi M, Koga Y, Kumagai R, Aishima S, Taguchi K, Oda Y.
Pathology International 2014 Apr; 64(4):155.
Application：IHC-P, Human, Intramucosal gastric cancer.
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The KHENERGY Study: Safety and Efficacy of KH176 in Mitochondrial m.3243A>G Spectrum Disorders.
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