PAFAH1B2 monoclonal antibody (M01A), clone 2F4-1C10
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant PAFAH1B2.
Immunogen
PAFAH1B2 (AAH00398, 1 a.a. ~ 229 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWRELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEAIVQLINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDTDGGFVHSDGAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEETPEEKQTTIA
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (99); Rat (99)
Isotype
IgM Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (50.93 KDa) .
Storage Buffer
In ascites fluid
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
PAFAH1B2 monoclonal antibody (M01A), clone 2F4-1C10. Western Blot analysis of PAFAH1B2 expression in human kidney.ELISA
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Gene Info — PAFAH1B2
Entrez GeneID
5049GeneBank Accession#
BC000398Protein Accession#
AAH00398Gene Name
PAFAH1B2
Gene Alias
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Gene Description
platelet-activating factor acetylhydrolase, isoform Ib, beta subunit 30kDa
Omim ID
602508Gene Ontology
HyperlinkGene Summary
Platelet-activating factor (PAF) is a biologically active phospholipid with diverse biologic effects. PAF is degraded to inactive products by hydrolysis of the acetyl group at the sn-2 position to produce the biologically inactive products LYSO-PAF and acetate. This reaction is catalyzed by PAF acetylhydrolase (PAFAH). The various monomeric and multimeric forms of the enzyme are composed of alpha (MIM 601545), beta, and gamma (MIM 603074) PAFAH subunits.[supplied by OMIM
Other Designations
intracellular platelet-activating factor acetylhydrolase alpha 2 subunit|platelet-activating factor acetylhydrolase IB subunit beta
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Interactome
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Pathway
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Disease
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