PA2G4 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human PA2G4 peptide using ARM Technology.
Immunogen
A synthetic peptide of human PA2G4 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human PA2G4 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — PA2G4
Entrez GeneID
5036GeneBank Accession#
PA2G4Gene Name
PA2G4
Gene Alias
EBP1, HG4-1, p38-2G4
Gene Description
proliferation-associated 2G4, 38kDa
Omim ID
602145Gene Ontology
HyperlinkGene Summary
This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified. [provided by RefSeq
Other Designations
ErbB-3 binding protein 1|ErbB3-binding protein 1|ErbB3-binding protein Ebp1|cell cycle protein p38-2G4 homolog
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Interactome
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Toll Free : +1-877-853-6098 - +1-909-992-3401
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