P2RY1 monoclonal antibody (M01), clone 4C2
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More Files
- More Functions
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged P2RY1 is approximately 1ng/ml as a capture antibody.
Immunofluorescence
Immunofluorescence of monoclonal antibody to P2RY1 on HeLa cell . [antibody concentration 10 ug/ml]
Western Blot detection against Immunogen (31.46 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant P2RY1.
Immunogen
P2RY1 (NP_002554, 1 a.a. ~ 52 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MTEVLWPAVPNGTDAAFLAGPGSSWGNSTVASTAAVSSSFKCALTKTGFQFY
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (88); Rat (87)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (31.46 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged P2RY1 is approximately 1ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to P2RY1 on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — P2RY1
Entrez GeneID
5028GeneBank Accession#
NM_002563Protein Accession#
NP_002554Gene Name
P2RY1
Gene Alias
P2Y1
Gene Description
purinergic receptor P2Y, G-protein coupled, 1
Omim ID
601167Gene Ontology
HyperlinkGene Summary
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq
Other Designations
ATP receptor|P2 purinoceptor subtype Y1|P2Y purinoceptor 1|platelet ADP receptor|purinergic receptor P2Y1
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Interactome
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Pathway
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Disease
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Publication Reference
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Altered distribution of small-conductance calcium-activated potassium channel SK3 in Hirschsprung's disease.
Coyle D, O’Donnell AM, Puri P.
Journal of Pediatric Surgery 2015 Oct; 50(10):1659.
Application：WB-Ce, Human, Colon sections, aganglionic specimen, ganglionic specimen.
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Altered distribution of small-conductance calcium-activated potassium channel SK3 in Hirschsprung's disease.
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