P2RX1 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human P2RX1 DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — P2RX1
Entrez GeneID
5023GeneBank Accession#
NM_002558.2Protein Accession#
NP_002549.1Gene Name
P2RX1
Gene Alias
P2X1
Gene Description
purinergic receptor P2X, ligand-gated ion channel, 1
Omim ID
600845Gene Ontology
HyperlinkGene Summary
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. It is possible that the development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill. [provided by RefSeq
Other Designations
ATP receptor|P2X purinoceptor 1|P2X receptor, subunit 1|P2X1 receptor|purinergic receptor P2X1
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Interactome
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Pathway
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