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Western Blot (Transfected lysate)

Western Blot analysis of SLC22A18 expression in transfected 293T cell line (H00005002-T01) by SLC22A18 MaxPab polyclonal antibody.

Lane 1: SLC22A18 transfected lysate(46.64 KDa).
Lane 2: Non-transfected lysate.

Entrez GeneID

5002

GeneBank Accession#

NM_002555.3

Protein Accession#

NP_002546.2

Gene Name

SLC22A18

Gene Alias

BWR1A, BWSCR1A, DKFZp667A184, HET, IMPT1, ITM, ORCTL2, SLC22A1L, TSSC5, p45-BWR1A

Gene Description

solute carrier family 22, member 18

Omim ID

114480 211980 268210 602631

Gene Ontology

Hyperlink

Gene Summary

This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region as well as the transport of chloroquine- and quinidine-related compounds in the kidney. Two alternative transcripts encoding the same isoform have been described. [provided by RefSeq

Other Designations

Beckwith-Wiedemann syndrome chromosome region 1, candidate A|OTTHUMP00000011732|OTTHUMP00000011733|efflux transporter-like protein|imprinted multi-membrane spanning polyspecific transporter-related protein|organic cation transporter-like 2|p45 Beckwith-Wi