ORC5L (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human ORC5L partial ORF ( NP_002544, 274 a.a. - 373 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
SSSQWEKLQKDDTDPGQLKGLSAHTHVELPYYSKFILIAAYLASYNPARTDKRFFLKHHGKIKKTNFLKKHEKTSNHLLGPKPFPLDRLLAILYSIVDSR
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (97); Rat (95)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — ORC5L
Entrez GeneID
5001GeneBank Accession#
NM_002553Protein Accession#
NP_002544Gene Name
ORC5L
Gene Alias
ORC5, ORC5P, ORC5T
Gene Description
origin recognition complex, subunit 5-like (yeast)
Omim ID
602331Gene Ontology
HyperlinkGene Summary
The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. It has been shown to form a core complex with ORC2L, -3L, and 4L. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq
Other Designations
origin recognition complex subunit 5
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Interactome
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Pathway
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Disease
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