ORC1L 293T Cell Transient Overexpression Lysate(Denatured)
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
SDS-PAGE Gel
ORC1L transfected lysate.
Western Blot
Lane 1: ORC1L transfected lysate ( 97.3 KDa)
Lane 2: Non-transfected lysate.
-
Specification
Transfected Cell Line
293T
Plasmid
pCMV-ORC1L full-length
Host
Human
Theoretical MW (kDa)
97.3
Interspecies Antigen Sequence
Mouse (66); Rat (69)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-ORC1L antibody (H00004998-B01) by Western Blots.
SDS-PAGE Gel
ORC1L transfected lysate.
Western Blot
Lane 1: ORC1L transfected lysate ( 97.3 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
-
Applications
Western Blot
-
Gene Info — ORC1L
Entrez GeneID
4998GeneBank Accession#
NM_004153Protein Accession#
NP_004144Gene Name
ORC1L
Gene Alias
HSORC1, ORC1, PARC1
Gene Description
origin recognition complex, subunit 1-like (yeast)
Omim ID
601902Gene Ontology
HyperlinkGene Summary
The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is the largest subunit of the ORC complex. While other ORC subunits are stable throughout the cell cycle, the levels of this protein vary during the cell cycle, which has been shown to be controlled by ubiquitin-mediated proteolysis after initiation of DNA replication. This protein is found to be selectively phosphorylated during mitosis. It is also reported to interact with MYST histone acetyltransferase 2 (MyST2/HBO1), a protein involved in control of transcription silencing. [provided by RefSeq
Other Designations
OTTHUMP00000009797|OTTHUMP00000009798|origin recognition complex 1|origin recognition complex, subunit 1|origin recognition complex, subunit 1, S. cerevisiae, homolog-like|replication control protein 1
-
Interactome
-
Pathway
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com