OPCML rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human OPCML peptide using ARM Technology.
Immunogen
A synthetic peptide of human OPCML is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human OPCML peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — OPCML
Entrez GeneID
4978GeneBank Accession#
OPCMLGene Name
OPCML
Gene Alias
IGLON1, OBCAM, OPCM
Gene Description
opioid binding protein/cell adhesion molecule-like
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily. The encoded protein is localized in the plasma membrane and may have an accessory role in opioid receptor function. This gene has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the encoded protein is highly conserved in species during evolution, it may have a fundamental role in mammalian systems. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
IgLON family member 1|opiate binding-cell adhesion molecule|opioid binding protein/cell adhesion molecule-like preprotein|opioid-binding protein/cell adhesion molecule-like
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Interactome
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Disease
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