OLR1 DNAxPab
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Specifications
Product Description
Rabbit polyclonal antibody raised against a full-length human OLR1 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MTFDDLKIQTVKDQPDEKSNGKKAKGLQFLYSPWWCLAAATLGVLCLGLVVTIMVLGMQLSQVSDLLTQEQANLTHQKKKLEGQISARQQAEEASQESENELKEMIETLARKLNEKSKEQMELHHQNLNLQETLKRVANCSAPCPQDWIWHGENCYLFSSGSFNWEKSQEKCLSLDAKLLKINSTADLDFIQQAISYSSFPFWMGLSRRNPSYPWLWEDGSPLMPHLFRVRGAVSQTYPSGTCAYIQRGAVYAENCILAAFSICQKKANLRAQ
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — OLR1
Entrez GeneID
4973GeneBank Accession#
NM_002543.2Protein Accession#
NP_002534.1Gene Name
OLR1
Gene Alias
CLEC8A, LOX1, SCARE1
Gene Description
oxidized low density lipoprotein (lectin-like) receptor 1
Omim ID
602601Gene Ontology
HyperlinkGene Summary
This gene encodes a receptor protein which belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternative transcript variants have been described but their full-length sequence has not been determined. [provided by RefSeq
Other Designations
lectin-type oxidized LDL receptor 1|oxidised low density lipoprotein (lectin-like) receptor 1|scavenger receptor class E, member 1
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Interactomes
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Pathways
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Diseases
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